Testosterone® is the
Diabetic Treatment
for Diabetic Men

Edward Lichten, M.D.,PC
180 East Brown Street
Birmingham, MI 48009 
248.593.9999

 

           Breakthrough in the Medical Treatment of Diabetic Men!
                  Could Lichten be a Nobel Prize candidate?

Testosterone replacement to diabetic men reduces the need for insulin, eliminates the need for expensive oral agents and improves glycemic control by reducing the risk of hypogylcemic crashes that may be life-threatening.

Dr. Edward Lichten announces the results of his 10-years of research in the American Medical News November 13, 2006 and has his keynote lecture to the American Academy of Anti-Aging Medicine on the internet.

OVERVIEW: 1998 Keynote Lecture 1997 DIABETIC PROTOCOL
INTRODUCTION: Data from Insulin Dependent Men
CHECKING diabetic LAB TESTS Non-insulin Dependent Men Data
**2007 NATIONAL LECTURE JAMA reference articles

In 1922, Banting and Best discovered insulin and changed the world of medicine. Not only did they discover a natural therapy to prevent death from diabetes, they gave away their patent to humanity. Today, 85 years later, we have proven that injectable testosterone is, in fact, more important than insulin because it is applicable to 5 times more diabetic men and another yet undiagnosed 10 fold.

In 1996, I discovered that my fasting insulin dropped from 10 miu/ml (borderline) to less than 2 while on injectable testosterone therapy. An adult diabetic male, J.N., 48 years old with confirmed abnormal glucose tolerance was able to lose 85 pounds in 10 months and regain his youthful physical, exercise and sexual vigor while on testosterone replacement. When retested at two years, his glucose tolerance was entirely normal.

This information and more gleaned from another 12 diabetic men and women convinced James Sowers, M.D., professor and chairman of metabolism and endocrinology to support a pilot study at Providence Hospital in Detroit in 1997. Project 607-97 showed
 

1. All diabetic men were hypogonadal based on measurement of total testosterone or bio-available T.

2. All men showed improvement in glycemic control on injectable testosterone therapy.
3. All men reported improvement in sexual function or less depression and improved sleep on injectables.
4. Two-thirds of the adult onset diabetic men, many who were diabetic for more than four years, showed a flat insulin response to the oral glucose given at the glucose tolerance test. These individuals uniformly stopped their prescription hypoglycemic medications without worsening their diabetic condition.

5. Parenteral testosterone lowered the need for insulin in the insulin dependent diabetics and improved the glycemic control in adult men after they had discontinued sulfonylurea medications.

The role of testosterone in diabetic men is to improve the transport of sugar (glucose) from the blood stream into the cell. If insulin is one of the two keys to the safety-box (cell), then
testosterone bound to SHBG is the other. Simply spoken, testosterone reduces the need for more and more insulin. And when the individual needs to raise sugar (glucose) from stored
fat, testosterone increases the glycogen-to-glucose conversion making glucose available averting a potential hypoglycemic crisis.
 

Therefore, there should be no fear about beginning testosterone injection replacement in diabetic men without the risk factors of elevated PSA, prostate or testicular cancer. Gels do not work! The skin aromatizes testosterone to estradiol worsening in time the estradiol/testosterone ratio and accelerating the progress to insulin resistance. Routine replacement for any man is 100mg IM weekly; Kapoor used 200mg IM every two weeks. We routinely use 150 mg weekly for men over 200 pounds and follow the testosterone, SHBG and estradiol every 6 weeks. Testosterone may raise hemoglobin so a donation of one unit to the Red Cross may be suggested every 3-4 months. Otherwise, few side-effects except increased libido, increased muscle mass, weight loss and drops in total cholesterol are usually reported.

References
1. JAMA CONFIRMS ALL DIABETIC MEN are HYPOGONADAL
 
JAMA 2006;295:1288-1299. EL Ding. Harvard. Boston USA. Cross-
sectional studies indicated that testosterone level was significantly lower in
men with type 2 diabetes ....Similarly, prospective studies showed that men
with higher testosterone levels (range, 449.6-605.2 ng/dL) had a 42% lower
risk of type 2 diabetes
 
2. EUROPEANS TREATS DIABETIC MEN WITH TESTOSTERONE
 
Kapoor D. Eur J Endocrinol 2006; 254(6): 899-906. Testosterone
replacement therapy improves insulin resistance, glycaemic control, visceral
adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes.

3. US RESEARCHERS show NANDRALONE, a 19-nortesteosterone, ENHANCES GLUCOSE UPTAKE in NORMAL MEN.
C, Jobbs, R.Jones and S. Plymate in JCEM 1996;81:1582-1585
We conclude that the treatment of normal men with supra-physiological doses of either Testosterone enanthate or Nandralone-decanoate, does not adversely affect glucose metabolism. treatment with a non-aromatizable androgen, such as ND, actually improves glucose metabolism by enhancing non-insulin-mediated glucose disposal.
 

 

 
 

Revised January 1, 2007